解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Single-walled carbon nanotubes (SWCNTs) are widely used in industrial and medical sectors, and the increasing exposure of SWCNTs necessitates the studies of their potential environmental and health effects. Considerable efforts have been made to improve the dispersion of SWCNTs by chemical modifications. However, the ...
journal_title:Nanotoxicology
pub_type: 杂志文章
doi:10.3109/17435390.2011.573101
更新日期:2012-05-01 00:00:00
abstract::With the advent of nanoparticles produced in high quantities and employed in products or processes, the need to evaluate their potential toxicological effects is necessary. For this purpose, biopersistence studies are needed to assess the possible effects of nanoparticles in parallel with a proper characterization. Th...
journal_title:Nanotoxicology
pub_type: 杂志文章
doi:10.3109/17435390.2011.572301
更新日期:2012-05-01 00:00:00
abstract::Abstract Nickel, zinc, and copper oxide nanoparticles (NiONP, ZnONP, and CuONP) and their aqueous extracts (AEs) were applied to A549 lung epithelial cells to determine the cytotoxicity, IL-8 production, and activation of transcription factors. Nanoparticles (NPs) and their AEs were also instilled into rat lungs to ...
journal_title:Nanotoxicology
pub_type: 杂志文章
doi:10.3109/17435390.2011.552810
更新日期:2012-02-01 00:00:00
abstract::Six TiO₂ and two CeO₂ nanomaterials with dry sizes ranging from 6-410 nm were tested for their ability to cause DNA centered free radicals in vitro in the concentration range of 10-3,000 ug/ml. All eight of the nanomaterials significantly increased the adduction of the spin trap agent 5,5-dimethyl-1-pyroline N-oxide (...
journal_title:Nanotoxicology
pub_type: 杂志文章
doi:10.3109/17435390.2010.539711
更新日期:2011-12-01 00:00:00
abstract::There is a paucity of data regarding the safety of administering solid gold nanoparticles (AuNPs) in large animal tumor models. We assessed the acute toxicity and biodistribution of 5 nm and 25 nm solid AuNPs in New Zealand White rabbits (n = 6 in each) with implanted liver Vx2 tumors 24 h after intravenous injection....
journal_title:Nanotoxicology
pub_type: 杂志文章
doi:10.3109/17435390.2010.516026
更新日期:2011-12-01 00:00:00
abstract::The use of imaging tools to probe nanoparticle-cell interactions will be crucial to elucidating the mechanisms of nanoparticle-induced toxicity. Of particular interest are mechanisms associated with cell penetration, translocation and subsequent accumulation inside the cell, or in cellular compartments. The objective ...
journal_title:Nanotoxicology
pub_type: 杂志文章,评审
doi:10.3109/17435390.2010.512987
更新日期:2011-09-01 00:00:00
abstract::Despite the wide use of silver nanoparticles (nano Ag), its toxicity still remains poorly understood. In this report, nano Ag induced an increase in platelet aggregation and procoagulant activation which are the key contributors to thrombotic diseases. In freshly isolated human platelets, nano Ag induced platelet aggr...
journal_title:Nanotoxicology
pub_type: 杂志文章
doi:10.3109/17435390.2010.506250
更新日期:2011-06-01 00:00:00
abstract::The addition of a transmitted electron detector to a scanning electron microscope (SEM) allows the recording of bright and dark field scanning transmission electron microscope (STEM) images and the corresponding in-lens secondary electron images from the same region of a thin sample. These combined imaging techniques ...
journal_title:Nanotoxicology
pub_type: 杂志文章
doi:10.3109/17435390.2010.535622
更新日期:2011-06-01 00:00:00
abstract::Deciphering the molecular basis of toxicology mechanism induced by nanoparticles (NPs) remains an essential challenge. Ion Beam Analysis (IBA) was applied in combination with Transmission Electron Microscopy and Confocal Microscopy to analyze human keratinocytes exposed to TiO(2)-NPs. Investigating chemical elemental ...
journal_title:Nanotoxicology
pub_type: 杂志文章
doi:10.3109/17435390.2010.502979
更新日期:2011-06-01 00:00:00
abstract::Cadmium (Cd) is a component in quantum dot 705 (QD705). Whether QD705 behaves similar to Cd in vivo is of great concern. We compared the distributional kinetics of cadmium chloride (CdCl(2)) and QD705 in mice after intravenous injection. QD705 showed a longer plasma and body retention than CdCl(2) and could be detecte...
journal_title:Nanotoxicology
pub_type: 杂志文章
doi:10.3109/17435390.2010.502260
更新日期:2011-03-01 00:00:00
abstract::If engineered nanomaterials are released into the environment, some are likely to end up associated with the food of animals due to aggregation and sorption processes. However, few studies have considered dietary exposure of nanomaterials. Here we show that zinc (Zn) from isotopically modified (67)ZnO particles is eff...
journal_title:Nanotoxicology
pub_type: 杂志文章
doi:10.3109/17435390.2010.501914
更新日期:2011-03-01 00:00:00
abstract::This study aims at investigating feasibility and challenges associated with conducting a human health risk assessment for nano-silver based on the open literature by following an approach similar to a classical regulatory risk assessment. Gaps in the available data set, both in relation to exposures and hazard, do not...
journal_title:Nanotoxicology
pub_type: 杂志文章
doi:10.3109/17435391003690549
更新日期:2010-09-01 00:00:00
abstract::Sunscreens containing metal oxide nanoparticles appear transparent on the skin and provide excellent protection against sunburn caused by UV radiation. While it is likely that nanoparticles remain on the surface of the skin of healthy adult humans, and thus are considered safe for use in sunscreens, there has been no ...
journal_title:Nanotoxicology
pub_type: 杂志文章,评审
doi:10.3109/17435390903502028
更新日期:2010-03-01 00:00:00